Synomag®-D and synomag®-S are prepared by a core-shell method. They consist of a core of maghemite with „nanoflower“ structure in a matrix of dextran (synomag®-D) or starch (synomag®-S). The unmodified particles are available with hydrodynamic diameters of 50 nm and 70 nm (synomag®-D) or 100 nm (synomag®-S). The particles cannot be separated with conventional permanent magnets, but in a high gradient magnetic field. They are delivered in water without any surfactants.

Renowed working groups have investigated the properties of synomag®-D particles under the names MM08 (Bender et al. 2018) or NF-2 (Gavilan et al. 2017). Synomag® particles are interesting tracers for Magnetic Particle Imaging (MPI) methods. The amplitude A3 of the 3rd harmonic in the MPS-spectrum of synomag®-D is more than twice as high compared to Resovist® (Grüttner et al. 2018).

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  • Bender, P., Fock, J., Frandsen, C., Hansen, M.F., Balceris, C., Ludwig, F., Posth, O., Wetterskog, E., Bogart, L.K., Southern, P., Szczerba, W., Zeng, L., Witte, K., Gruettner, C., Westphal, F., Honecker, D., González-Alonso, D., Fernández Barquín, L., and Johansson, C., Relating Magnetic Properties and High Hyperthermia Performance of Iron Oxide Nanoflowers, The Journal of Physical Chemistry C, 2017, doi: 10.1021/acs.jpcc.7b11255;
  • Gavilán, H., Kowalski, A., Heinke, D., Sugunan, A., Sommertune, J., Varón, M., Bogart, L.K., Posth, O., Zeng, L., González-Alonso, D., Balceris, C., Fock, J., Wetterskog, E., Frandsen, C., Gehrke, N., Grüttner, C., Fornara, A., Ludwig, F., Veintemillas- Verdaguer, S., Johansson, C., and Puerto Morales, M., Colloidal Flower-Shaped Iron Oxide Nanoparticles: Synthesis Strategies and Coatings, Particle & Particle Systems Characterization, 2017, 1700094 doi: 10.1002/ppsc.201700094;