PLA-M particles

Magnetic poly(lactic acid) particles (PLA-M particles)

PLA-M particles consist of magnetite (40% w/w) in a matrix of poly(D,L-lactic acid) with a molecular weight of 17.000 Da. They are available with mean diameters of 30 µm, 50 µm and 100 µm and a plain surface or with carboxylic acid groups on the surface.

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References
  • C. Grüttner, K. Müller and J. Teller, A rapid assay to measure the shielding of iron oxide cores by the particle shell, IEEE Trans. Magn., 2013, 49(1), 177–181;
  • A. J. Lehtonen, O. Arasalo, L. Srbova, M. Heilala and J. Pokki, Magnetic microrheometry of tumor-relevant stiffness levels and probabilistic quantification of viscoelasticity differences inside 3D cell culture matrices, PloS one, 2023, 18(3), e0282511;
  • Y. Mima, S. Fukumoto, H. Koyama, M. Okada, S. Tanaka, T. Shoji, M. Emoto, T. Furuzono, Y. Nishizawa and M. Inaba, Enhancement of cell-based therapeutic angiogenesis using a novel type of injectable scaffolds of hydroxyapatite-polymer nanocomposite microspheres, PLoS One, 2012, 7(4), e35199;
  • G. Mistlberger and I. Klimant, Luminescent magnetic particles: structures, syntheses, multimodal imaging, and analytical applications, Bioanal Rev, 2010, 2(61–101;
  • H. Kuramitz, Magnetic microbead-based electrochemical immunoassays, Anal Bioanal Chem, 2009, 394(61–69;
  • M. Thongkham, S. Hongsibsong, S. Mekchay, A. Sathanawongs, P. Paitoon, A. Saenjaiban, A. Satsook, K. Jantanasakulwong, P. Rachtanapun, Z.-L. Xu and K. Sringarm, Revolutionizing sexed sorting sperm using scFv antibodies combined with microbeads for porcine sexed semen, International Journal of Biological Macromolecules, 2025, 308(142477;
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