nanomag®-CLD

Cross-linked magnetic dextran nanoparticles (nanomag®-CLD)

  • are prepared via the core-shell method with a core of magnetite and a dextran shell,
  • are available with particle diameters of 300 nm and 500 nm for separation with a permanent magnet,
  • consist of 80-90% (w/w) magnetite in a matrix of crosslinked dextran,
  • are designed with NH2, COOH and PEG-COOH for the covalent binding of proteins, antibodies or other molecules,
  • are available with covalently bound streptavidin,
  • other protein surfaces are available on request.

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References
  • R. Rasouli, C. Grüttner, M. S. Ardestani and R. Faridi-Majidi, Preparation and Evaluation of New LAT1-Targeted USPION to Improve Sensitivity and Specificity in Metabolic Magnetic Imaging of Breast Cancer, Biointerface Research in Applied Chemistry, 2021, 10248–10264;
  • Kanazaki, K., Honma, T., Yamauchi, F., Ogawa, S., and Inoue, S., Composite particle, contrast agent for photoacoustic imaging and method for producting the composite particle, US 0294987, 2011;
  • E. Fernandes, T. Sobrino, V. C. Martins, I. Lopez-Loureiro, F. Campos, J. Germano, M. Rodríguez-Pérez, S. Cardoso, D. Y. Petrovykh and J. Castillo, Point-of-care quantification of serum cellular fibronectin levels for stratification of ischemic stroke patients, Nanomedicine: Nanotechnology, Biology and Medicine, 2020, 30(102287;
  • A. M. Pourshahidi, S. Achtsnicht, M. M. Nambipareechee, A. Offenhäusser and H.-J. Krause, Multiplex Detection of Magnetic Beads Using Offset Field Dependent Frequency Mixing Magnetic Detection, Sensors, 2021, 21(17), 5859;
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