Plain

Synomag®-D und synomag®-S werden mittels Core-Shell-Verfahren hergestellt. Sie besitzen einen Maghemit-Kern mit „Nanoflower“-Struktur, welcher in einer Matrix aus Dextran oder Stärke eingebettet ist. Die unmodifizierten Oberflächen sind mit einem hydrodynamischen Durchmesser von 50 nm und 70 nm (synomag®-D) bzw. 100 nm (synomag®-S) erhältlich. Synomag®-D- und synomag®-S-Partikel können nicht mit am Permanentmagneten, sondern nur in einem Hochgradientenmagnetfeld separiert werden. Sie werden in Wasser ohne Zusatz von Detergenzien geliefert.

Synomag®-D-Partikel wurden in der Entwicklungsphase von verschiedenen Arbeitsgruppen unter den Namen MM08 (Bender et al. 2018) bzw. NF-2 (Gavilan et al. 2017) charakterisiert. Synomag®-D-Partikel sind effektive Forschungstracer für das Magnetic Particle Imaging (MPI). Die Amplitude A3 der 3. Harmonischen im MPS-Spektrum von synomag®-D ist mehr als zweimal so hoch im Vergleich zu Resovist® (Grüttner et al. 2018).

Alle 3 Ergebnisse werden angezeigt

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