PEG-COOH

micromer®-M particles are designed with PEG-COOH groups in the whole size range of 2 µm to 10 µm. The particles are stable in aqueous media and to some extend in DMSO. They are supplied in water without any surfactants.  Thus the particles can be directly applied for the covalent binding of proteins, antibodies or other target molecules, e.g. after carbodiimide activation of the COOH groups (see Technote 200).

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References
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  • Ehresmann, A., Method and Apparatus for transporting magnetic fluids and particles, 2011, WO 054391 A1;
  • Kuramitz, H., Magnetic microbead-based electrochemical immunoassays, Anal Bioanal Chem, 2009, 394, 61-9;
  • Moser, C., Mayr, T., and Klimant, I., Filter cubes with built- in ultrabright light- emitting diodes as exchangeable excitation light sources in fluorescence microscopy, Journal of Microscopy, 2006, 222, 135- 40;
  • Penchovsky, R., and McCaskill, J.S., Cascadable hybridisation transfer of specific DNA between microreactor selection modules, DNA 7, LNCS 2340, 2002, N. Jonoska and N.C. Seeman (Eds.), 46-56;
  • Recker, T., Haamann, D., Schmitt, A., Küster, A., Klee, D., Barth, S., and Müller-Newen, G., Directed covalent immobilization of fluorescently labeled cytokines, Bioconjugate chemistry, 2011, 22(6), 1210-20;