PEG-NH2

micromer®-M particles are designed with  PEG-NH2 groups on the surface for the covalent binding of proteins, antibodies or other target molecules. The particles are stable in aqueous media and to some extend in DMSO. They are supplied in water without any surfactants. Thus the whole variety of conjugation methods can be directly applied, e.g. maleimide or SPDP functionalization of the amino groups for conjugation of SH-labeled biomolecules.

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References
  • Eriksson, K., Palmgren, P., Nyholm, L., and Oscarsson, S., Electrochemical synthesis of gold and protein gradients on particle surfaces, Langmuir, 2012, 28, 10318-23;
  • Johansson, L.E., Gunnarsson, K., Bijelovic, S., Eriksson, K., Surpi, A., Göthelid, E., Svedlindh, P., and Oscarsson, S., A magnetic microchip for controlled transport of attomole levels of proteins, Lab Chip, 2010, 10, 654-61;
  • Oscarsson, S., Nyholm, L., Svedlindh, P., and Gunnarsson, K., Partial derivatization of particles, US 0003401, 2011;