NH2

Cluster-typed magnetic silica particles (sicastar®-M-CT) with amino groups on the surface and a mean diameter of 6 microns are available for the covalent binding of proteins, antibodies or other molecules.
The particles are stable in aqueous and in organic media and allow the binding of water-soluble molecules as well as of molecules, that are only soluble in organic solvents. The functionalized particles are supplied in water.

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References
  • V. Böhmer, J.-F. Dozol, C. Grüttner, K. Liger, S. E. Matthews, S. Rudershausen, M. Saadioui and P. Wang, Separation of lanthanides and actinides using magnetic silica particles bearing covalently attached tetra-CMPO-calix[4]arenes, Org. Biomol. Chem., 2004, 2(2327–2334;
  • C. Grüttner, V. Böhmer, A. Casnati, J.-F. Dozol, D. N. Reinhoudt, M. M. Reinoso-Garcia, S. Rudershausen, J. Teller, R. Ungaro and W. Verboom, Dendrimer-coated magnetic particles for radionuclide separation, Journal of magnetism and magnetic materials, 2005, 293(1), 559–566;
  • C. Grüttner, S. Rudershausen, S. Matthews, P. Wang, V. Böhmer and J. Dozol, Selective extraction of lanthanides and actinides by magnetic silica particles with CMPO-modified calix [4] arenes on the surface, European Cells and Materials, 2002, 3(2), 48–51;
  • S. E. Matthews, P. Parzuchowski, A. Garcia-Carrera, C. Grüttner, J.-F. Dozol and V. Böhmer, Extraction of lanthanides and actinides by a magnetically assisted chemical separation technique based on CMPO-calix [4] arenesElectronic supplementary information (ESI) available: full synthetic procedures and extraction studies. See http://www. rsc. org/suppdata/cc/b0/b009679m, Chemical Communications, 2001, 5), 417–418;
  • M. M. Reinoso-García, D. Jańczewski, D. N. Reinhoudt, W. Verboom, E. Malinowska, M. Pietrzak, C. Hill, J. Báča, B. Grüner and P. Selucky, CMP (O) tripodands: synthesis, potentiometric studies and extractions, New journal of chemistry, 2006, 30(10), 1480–1492;