COOH

sicastar®-Partikel sind mit Carbonsäuregruppen (COOH) auf der Oberfläche im Größenbereich von 50 nm bis 20 µm erhältlich. Zur kovalenten Bindung von Proteinen, Antikörpern oder anderen Zielmolekülen kann z. B. die  Carbodiimid-Aktivierung von COOH-Gruppen zur Konjugation an Aminogruppen verwendet werden (siehe Technote 200).
Die Partikel werden als Suspension in Wasser ohne Zusatz von Detergenzien geliefert.

Showing all 12 results

Referenzen
  • Claudet, C., Angelov, D., Bouvet, P., Dimitrov, S., and Bednar, J., Histone octamer instability under single molecule experiment conditions, J Biol Chem, 2005, 280(20), 19958-65;
  • Delport, F., Deres, A., Hotta, J.-i., Pollet, J., and al., e., Improved methods for counting DNA molecules on biofunctionalized nanoparticles, Langmuir, 2010, 26(3), 1594-7;
  • Guthaus, E., Bürgle, M., Schmiedeberg, N., Hocke, S., Eickler, A., Kramer, M.D., Sweep, C.G.J.F., Magdolen, V., Kessler, H., and Schmitt, M., uPA-Silica-Particles (SP-uPA): A novel analytical system to investigate uPA-uPAR-interaction and to test synthetic uPAR-antagonists as potential cancer therapeutics, Biolog Chem, 2002, 383(1), 207-16;
  • Guthaus, E., Schmiedeberg, N., Bürgle, M., Magdolen, V., Kessler, H., and Schmitt, M., The urokinase receptor (uPAR, CD87) as a target for tumor therapy: uPA-Silica-Particles (SP-uPA) as a new tool to assess synthetic peptides to interfere with uPA/uPA-receptor interaction (Review), Recent Results Cancer Res, 2003, 162, 3-14;
  • Hata, K., Higashisaka, K., Nagano, K., Mukai, Y., Kamada, H., Tsunoda, S.-i., Yoshioka, Y., and Tsutsumi, Y., Evaluation of silica nanoparticle binding to major human blood proteins, Nanoscale Research Letters, 2014, 9(1), 668;
  • Higashisaka, K., Yoshioka, Y., Yamashita, K., Morishita, Y., Pan, H., Ogura, T., Nagano, T., Kunieda, A., Nagano, K., Abe, Y., Kamada, H., Tsunoda, S.-i., Nabeshi, H., Yoshikawa, T., and Tsutsumi, Y., Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles, Nanoscale Res Lett, 2012, 7, 555;
  • Morishige, T., Yoshioka, Y., Inakura, H., Tanabe, A., Yao, X., Tsunoda, S., Tsutsumi, Y., Mukai, Y., Okada, N., and Nakagawa, S., Cytotoxicity of amorphous silica particles against macrophage-like THP-1 cells depends on particle-size and surface properties, Die Pharmazie-An International Journal of Pharmaceutical Sciences, 2010, 65(8), 596-9;
  • Pang, L., Farkas, K., Bennett, G., Varsani, A., Easingwood, R., Tilley, R., Nowostawska, U., and Lin, S., Mimicking filtration and transport of rotavirus and adenovirus in sand media using DNA-labeled, protein-coated silica nanoparticles, Water research, 2014, 62, 167-79;