COOH

micromer® particles are designed with COOH groups on the surface in the whole size range of 25 nm to 100 µm. The particles are stable in aqueous media and to some extend in DMSO. The particles are supplied in water without any surfactants. Thus the whole variety of conjugation methods for the covalent binding of proteins, antibodies or other target molecules can be applied, e.g. the carbodiimide activation of COOH groups for conjugation to amino groups (see Technote 200).

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References
  • Sato, H., Masubuchi, Y., and Watanabe, H., DNA diffusion in aqueous solution in presence of suspended particles, Journal of Polymer Science Part B: Polymer Physics, 2009, 47(11), 1103-11;
  • Wattendorf, U., Towards receptor-specific targeting of antigen presenting cells with functionalized stealth microparticles, PhD thesis, 2008;