NH2

sicastar® particles are available with amino groups (NH2) on the surface in the size range from 50 nm to 20 µm. For the covalent binding of proteins, antibodies or other target molecules various conjugation methods can be applied e.g. the SPDP or maleimide functionalization for conjugation of thiolated molecules.
The particles are delivered in aqueous suspension without any surfactants.

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References
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  • T. Morishige, Y. Yoshioka, H. Inakura, A. Tanabe, X. Yao, S. Tsunoda, Y. Tsutsumi, Y. Mukai, N. Okada and S. Nakagawa, Cytotoxicity of amorphous silica particles against macrophage-like THP-1 cells depends on particle-size and surface properties, Die Pharmazie-An International Journal of Pharmaceutical Sciences, 2010, 65(8), 596–599;
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  • G. Willmott, R. Vogel, S. Yu, L. Groenewegen, G. Roberts, D. Kozak, W. Anderson and M. Trau, Use of tunable nanopore blockade rates to investigate colloidal dispersions, Journal of Physics: Condensed Matter, 2010, 22(45), 454116;