synomag®-CLD-F

Fluorescent magnetic nanoparticles with „Nanoflower“ structure (synomag®-CLD-F)

  • combine sophisticated magnetic properties and detection purposes,
  • are available with red (excitation: 570 nm, emission: 600 nm) and far-red fluorescence (excitation: 730 nm, emission: 765 nm),
  • show specific interaction with alternating magnetic fields,
  • are excellent tracers for Magnetic Particle Imaging (MPI),
  • are available with hydrodynamic particle diameters of 50 nm and 70 nm,
  • consist of maghemite in a matrix of crosslinked dextran (40.000 Da) and cannot be separated with a conventional permanent magnet but in a high gradient magnetic field,
  • are provided with a plain surface or with amino groups on the surface for the covalent binding of proteins, antibodies or other molecules.

 

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References
  • A. Dinari, H. A. Ahmad, S. Oh, Y.-H. Kim and J. Yoon, Advanced detection of pancreatic cancer circulating tumor cells using biomarkers and magnetic particle spectroscopy, Nanotheranostics, 2025, 9(2), 171;
  • M. Koh, J. E. Lee, E. Ye, S. Lee, H.-L. Kim, H. E. Song, H. J. Yoo, W. J. Kim, S.-M. Park and S. H. Yang, Intranasal administration of temozolomide conjugated nanoparticles with transcranial magnetic stimulation improves the survival in glioblastoma xenograft models, Drug Delivery and Translational Research, 2026, 16(2), 509–521;
  • I. P. Novoselova, A. Neusch, J.-S. Brand, M. Otten, M. R. Safari, N. Bartels, M. Karg, M. Farle, U. Wiedwald and C. Monzel, Magnetic Nanoprobes for Spatio-Mechanical Manipulation in Single Cells, Nanomaterials, 2021, 11(9), 2267;
  • E. Ye, E. Park, E. Kim, J. E. Lee, S. H. Yang and S.-M. Park, Transcranial application of magnetic pulses for improving brain drug delivery efficiency via intranasal injection of magnetic nanoparticles, Biomedical Engineering Letters, 2023, 1–11;
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