Fluorescent silica particles (sicastar®-F) with carboxylic acid groups (COOH) on the surface are designed for the covalent binding of proteins, antibodies, oligonucleotides, enzymes or other molecules. The fluorescent silica particles are monodisperse and nonporous in the size range of 50 nm to 1,5 µm with a density of 2.0 g/cm³. They have broader size distributions in the area of the porous silica particles with adjusted diameters between 3 and 20 microns and a density of 1.8 g/cm³. The particles are available with red fluorescence (sicastar®-redF, excitation: 569 nm, emission: 585 nm), with green fluorescence (sicastar®-greenF, excitation: 485 nm, emission: 510 nm) or with blue fluorescence (sicastar®-blueF, excitation: 354 nm, emission: 450 nm).
Silica particles with special fluorescent properties are available on request. The particles are delivered in aqueous suspension without any surfactants.

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  • Freese, C., Schreiner, D., Anspach, L., Bantz, C., Maskos, M., Unger, R.E., and Kirkpatrick, C.J., In vitro investigation of silica nanoparticle uptake into human endothelial cells under physiological cyclic stretch, Particle and fibre toxicology, 2014, 11(1), 68;
  • Howorka, S., and Pammer, P., Molecule arrays and method for producing the same, WO/2005/025737, 2005;
  • Kasper, J.Y., Feiden, L., Hermanns, M.I., Bantz, C., Maskos, M., Unger, R.E., and Kirkpatrick, C.J., Pulmonary surfactant augments cytotoxicity of silica nanoparticles: Studies on an in vitro air–blood barrier model, Beilstein Journal of Nanotechnology, 2015, 6, 517-28, doi: 10.3762/bjnano.6.54;
  • Schiperski, F., Zirlewagen, J., and Scheytt, T., Transport and attenuation of particles of different density and surface charge: A karst aquifer field study, Environmental science & technology, 2016, 50(15), 8028-35;