plain

Plain poly(lactic acid) (PLA) particles consist of poly(D,L-lactic acid) with a molecular weight of 17.000 D. They are available with diameters of 250 nm and 500 nm in small size distributions and with mean diameters of 30 µm and 100 µm in broader size distributions. The particles are supplied in water without any surfactants.

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References
  • Luderer, F., Löbler, M., Rohm, H.W., Gocke, C., Kunna, K., Köck, K., Kroemer, H.K., Weitschies, W., Schmitz, K.-P., and Sternberg, K., Biodegradable Sirolimus- loaded Poly(lactide) Nanoparticles as Drug Delivery System for the Prevention of In-Stent Restenosis in Coronary Stent Application, J Biomater Appl, 2011, 25, 851-75;
  • Mima, Y., Fukumoto, S., Koyama, H., Okada, M., Tanaka, S., Shoji, T., Emoto, M., Furuzono, T., Nishizawa, Y., and Inaba, M., Enhancement of cell-based therapeutic angiogenesis using a novel type of injectable scaffolds of hydroxyapatite-polymer nanocomposite microspheres, PLoS One, 2012, 7(4), e35199;
  • Moeller, S., Kegler, R., Sternberg, K., and Mundkowski, R.G., Influence of sirolimus-loaded nanoparticles on physiological functions of native human polymorphonuclear neutrophils, Nanomedicine: Nanotechnology, Biology and Medicine, 2012, 8(8), 1293-300;
  • Weidmann, A., Kwittner, S., Beck, R., Teller, J., Jonas, L., and Nebe, B.J., Prevention of Lens Epithelial Cell Growth In Vitro Using Mibefradil- Containing PLGA Micro Particles, The Open Ophthalmology Journal, 2008, 2, 112- 8;