COOH

Perimag® particles with a diameter of 130 nm are designed with carboxylic acid groups on the surface for the covalent binding of proteins, antibodies or other molecules, e.g. by carbodiimide chemistry (see technote 200). The perimag® particles cannot be separated with conventional permanent magnets, but in a high gradient magnetic field. The functionalized perimag® particles are supplied in water without any surfactants.

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References
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  • O. Buchholz, K. Sajjamark, J. Franke, H. Wei, A. Behrends, C. Münkel, C. Grüttner, P. Levan, D. von Elverfeldt and M. Graeser, In situ theranostic platform combining highly localized magnetic fluid hyperthermia, magnetic particle imaging, and thermometry in 3D, Theranostics, 2024, 14(1), 324;
  • T. J. Carter, G. Agliardi, F. Y. Lin, M. Ellis, C. Jones, M. Robson, A. Richard‐Londt, P. Southern, M. Lythgoe and M. Zaw Thin, Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation, Small, 2021, 17(14), 2005241;