PEG-NH2

BNF-Dextran or BNF-Starch particles are available with PEG-NH2 groups on the surface for the covalent binding of proteins, antibodies or other molecules. The matrix of the functionalized particles consists of crosslinked dextran or hydroxyethyl starch. The 100 nm particles can be separated with conventional permanent magnets, while the 80 nm particles have to be separated in high gradient magnetic fields. BNF-Starch particles can easily be filtered through 0.22 µm filters. They are supplied in water without any surfactants. The BNF particles can be provided with covalently bound antibodies on request.

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References
  • Al Faraj, A., Shaik, A., Afzal, S., Al-Muhsen, S., and Halwani, R., Specific targeting and noninvasive magnetic resonance imaging of an asthma biomarker in the lung using polyethylene glycol functionalized magnetic nanocarriers, Contrast media & molecular imaging, 2015;